isibhengezo_sekhasi

138774-98-8 Boc-N-Me-D-Tyr(bzl)-OH

138774-98-8 Boc-N-Me-D-Tyr(bzl)-OH

Incazelo emfushane:

Ukubukeka Impushana emhlophe ukuya kokumhlophe
MF I-C22H27NO5
MW 385.45
Ubumsulwa 98+


Imininingwane Yomkhiqizo

Isimo sezokuthutha
Kungaba kuzinga lokushisa elijwayelekile

Ncoma indlela yokuthumela
Ngomoya Ngomhlaba Ngasolwandle

Isimo sesitoreji:
Gcina endaweni emnyama, emkhathini ongangeni, izinga lokushisa legumbi

Impilo yeshelufu
Cishe iminyaka emi-2

Ubuncane be-oda Ubuningi:
1kg (ingxoxo)

Isitifiketi:I-COA, indawo encibilikayo, i-SpecificRotation [α]D20                      

Sizothumela noma iyiphi idatha oyifunayo.Ungabona idatha ngaphambili njengereferensi.

Ngemikhiqizo eyenziwe ngokwezifiso, sithumela idatha entsha kakhulu ngemuva kokuthi iphumile.

I-D-Ls(tfa)-NCA (2)

Omqondofana

I-N-alpha-(t-Butyloxycarbonyl)-N-alpha-methyl-O-benzyl-D-tyrosine;

N- [(1,1-Dimethylethoxy)carbonyl]-N-methyl-O-(phenylmethyl)-D-tyrosine;

I-N-Boc-N-methyl-O-benzyl-D-tyrosine;

BOC-N-METHYL-O-BENZYL-D-TYROSINE;

I-BOC-N-ME-D-TYR(BZL)-OH;

I-BOC-N-ME-D-TYROSINE(BZL)-OH;

BOC-N-ALPHA-METHYL-O-BENZYL-D-TYROSINE;

I-BOC-D-METYR(BZL)-OH

Ukupakisha kwangaphakathi

Zivame ukusetshenziselwa ukupakisha impushana.Kuya ngemfuneko yamakhasimende.Ngakho-ke, sitshele ngenkani yakho ngaphambi kokupakisha uma unezicelo ezikhethekile.

Ukupakisha kwangaphakathi 2
Ukupakisha kwangaphakathi 1
Ukupakisha kwangaphakathi 3

ukupakisha kwangaphandle

1kg kuya ku-25kg Ukupakisha kwangaphandle kunzima.Futhi kunzima ukusika nokulimaza.Ingavikela imikhiqizo yakho ngokuphelele.

Ukupakisha kwangaphandle 3
Ukupakisha kwangaphandle 2
Ukupakisha kwangaphandle 1

Izinhlelo zokusebenza

I-Boc-N-Me-D-Tyr(Bzl)-OH, eyaziwa nangokuthi i-N-α-(tert-butyloxycarbonyl)-N-α-methyl-D-tyrosine benzyl ester, iphuma e-amino acid evikelwe esetshenziswa ngokuyinhloko ku-peptide. ukuhlanganisa.Le nhlanganisela ihlanganisa amaqembu amabili okuzivikela: i-Boc (tert-butyloxycarbonyl) ye-amino terminus ne-benzyl (Bzl) yeqembu le-phenolic hydroxyl ye-D-tyrosine.

Iqembu le-Boc livikela i-amino terminus, livimbele ukusabela okungafuneki phakathi nenqubo ye-peptide synthesis.I-benzyl ester ivikela iqembu le-phenolic hydroxyl, iqinisa inhlanganisela futhi iqinisekise ukuhlanzeka kwayo ngesikhathi sokugcina nokuphatha.

Ukusetshenziswa okuyinhloko kwe-Boc-N-Me-D-Tyr(Bzl)-OH kusekuhlanganiseni kwe-peptide yesigaba esiqinile, lapho kusebenza khona njengebhlokhi yokwakha yokuhlanganisa ama-peptide aqukethe i-D-tyrosine.I-D-tyrosine iyi-amino acid engeyona eyemvelo engafakwa kuma-peptide ukuze kufundwe izakhiwo zawo zebhayoloji noma ukwenza ama-peptide analogue anemisebenzi eguquliwe.

Ngokusebenzisa i-Boc-N-Me-D-Tyr(Bzl)-OH, abacwaningi bangakwazi ukwethula i-D-tyrosine ngawo womabili amaqembu e-amino ne-phenolic hydroxyl avikelwe ekulandeleni kwawo ama-peptide.Lokhu kuvumela ukulawula okunembile phezu kwesakhiwo se-peptide ngesikhathi sokuhlanganiswa futhi kusiza ukwethulwa kwamanye ama-amino acid nokuguqulwa ezindaweni ezithile ngaphakathi kweketango le-peptide.

Ngokungeziwe ekusebenziseni kwayo ekuhlanganiseni kwe-peptide, i-Boc-N-Me-D-Tyr(Bzl)-OH ingase futhi ithole izinhlelo zokusebenza kweminye imikhakha ye-biochemistry kanye ne-biotechnology, njengokwakhiwa kwemithi emisha noma ama-ejenti okwelapha.

imikhiqizo ehlobene

N-Me-Tyr(Me)-OH.HCl I-Boc-N-Me-L-Tyr(tbu)-OH I-Fmoc-N-Me-L-Tyr(tBu)-OH Cbz-N-Me-Tyr(tbu)-OH
I-Fmoc-N-Me-D-Tyr(tBu)-OH I-Boc-N-Me-L-Tyr(bzl)-OH I-Fmoc-N-Me-L-Tyr(bzl)-OH FMOC-N-Me-D-Tyr(mina)-OH

Kungani Khetha Thina

1. Mayelana ne-MOQ: Singayilungisa ngokuvumelana nemfuneko yakho.
2. Mayelana nesampula: Isampula idinga imali yesampula, okungaba yimpahla ongayilanda noma ongayikhokha kithi kusengaphambili.
3. I-Mold workshop, ingenziwa ngezifiso ngokusho kwenani lamamodeli.
4. Sinikeza isevisi engcono kakhulu.Ithimba labadayisi abanolwazi selisebenzela wena.
5. Mayelana nokushintshisana: Ngicela ungithumele i-imeyili noma ungixoxele ngesikhathi esivumelana nawe.


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