isibhengezo_sekhasi

23680-31-1 Tert-butoxycarbonyl-serine(Benzyl)-OH

23680-31-1 Tert-butoxycarbonyl-serine(Benzyl)-OH

Incazelo emfushane:

Ukubukeka Amakristalu amhlophe kuya kokumhlophe noma impushana ecwebezelayo
MF I-C15H21NO5
MW 295.33
Ubumsulwa 98+


Imininingwane Yomkhiqizo

Isimo sezokuthutha
Kungaba kuzinga lokushisa elijwayelekile

Ncoma indlela yokuthumela
Ngomoya Ngomhlaba Ngasolwandle

Isimo sesitoreji:
Gcina endaweni emnyama, emkhathini ongangeni, izinga lokushisa legumbi

Impilo yeshelufu
Cishe iminyaka emi-2

Ubuncane be-oda Ubuningi:
1kg (ingxoxo)

Isitifiketi:I-COA, indawo encibilikayo, i-SpecificRotation [α]D20                      

Sizothumela noma iyiphi idatha oyifunayo.Ungabona idatha ngaphambili njengereferensi.

Ngemikhiqizo eyenziwe ngokwezifiso, sithumela idatha entsha kakhulu ngemuva kokuthi iphumile.

I-D-Ls(tfa)-NCA (2)

Omqondofana

N-BOC-O-Benzyl-L-ser;
I-N-Boc-O-benzyl-L-serineBoc-Ser(Bzl)-OH;
(S)-3-(benzyloxy)-2-((tert-butoxycarbonyl)aMino)propanoicacid;
N-BOC-O-BENZYL-SERINE;
(2S)-3-Benzyloxy-2-(tert-butoxycarbonylamino)propanoicacid;
L-SERINE-NT-BOC,O-BZETHER(15N);
I-L-SERINE-NT-BOC,O-BZETHER(2-13C)

Ukupakisha kwangaphakathi

Ngokuvamile zisetshenziselwa ukupakisha izimpushana.Kuya ngezidingo zekhasimende.Ngakho-ke, uma unezidingo ezikhethekile, sicela usazise izidingo zakho ngaphambi kokupakisha.

Ukupakisha kwangaphakathi 2
Ukupakisha kwangaphakathi 1
Ukupakisha kwangaphakathi 3

ukupakisha kwangaphandle

Iphakheji yangaphandle inzima kakhulu.Futhi akulula ukusikwa nokulimala.Ingavikela imikhiqizo yakho ngokuphelele.

Ukupakisha kwangaphandle 3
Ukupakisha kwangaphandle 2
Ukupakisha kwangaphandle 1

Izinhlelo zokusebenza

I-Peptide Synthesis:

I-Boc-Ser(Bzl)-OH isebenza njengebhlokhi yokwakha esigabeni esiqinile noma ekuhlanganiseni kwe-peptide kwesigaba sesixazululo.Ingahlanganiswa namanye ama-amino acid noma izingcezu ze-peptide ukwenza ama-peptide amade noma amaprotheni.
Iqembu le-benzyl (Bzl) livikela iqembu le-hydroxyl le-serine, livumela ukusabela okukhethiwe kwamanye amasayithi ngaphakathi kweketango le-peptide.
Iqembu le-Boc livikela iqembu le-amino, livimbela ukusabela okungafuneki ohlangothini ngesikhathi sokuhlanganiswa kwe-peptide.
Izifundo ze-Biochemical:

I-Boc-Ser(Bzl)-OH ingasetshenziswa njenge-reagent ekuhlolweni kwamakhemikhali ezinto eziphilayo ukuze kufundwe ukusebenzisana kwamaprotheni-amaprotheni, i-enzyme kinetics, nezinye izinhlelo zokusebenza zebhayoloji yamangqamuzana.
Ngokuhlanganisa lokhu kuphuma kokuphuma kwe-amino acid kuma-peptide noma amaprotheni, abacwaningi bangaphenya ukusebenza kwawo kanye nokusebenzisana namanye ama-molecule ebhayoloji.
Ukutholwa Kwezidakamizwa:

I-Boc-Ser(Bzl)-OH ingafakwa emithini ye-peptidomimetics noma ye-peptide, eklanyelwe ukulingisa imisebenzi yebhayoloji yama-peptide emvelo.
Lawa ma-peptidomimetics angase abe namandla okwelapha ezindaweni ezinjengomdlavuza, izifo ezithathelwanayo, nokuphazamiseka kwemizwa.
Iqembu le-benzyl lingasuswa ngesikhathi sokuthuthukiswa kwezidakamizwa ukuze kwembule iqembu lamahhala le-hydroxyl le-serine, elingase libe semqoka emsebenzini webhayoloji we-peptide.
Isayensi Yezinto Ezibalulekile:

I-Boc-Ser(Bzl)-OH ingasetshenziswa ekuhlanganiseni ama-polymers ahambisana ne-biocompatible kanye ne-biodegradable for tissue engineering, ukulethwa kwezidakamizwa, nezinye izinhlelo zokusebenza ze-biomedical.
Lawa ma-polymers angaklanywa ukuthi akhiphe izidakamizwa noma ama-molecule e-bioactive ngendlela elawulwayo, athuthukise ukusebenza kahle kwawo kokwelapha kanye nokunciphisa imiphumela engemihle.

imikhiqizo ehlobene

I-L-Ser H-DL-Ser-OH I-D-Ser(tBu)-OH
I-D-Ser(bzl) I-D-Ser(bzl).HCl I-HL-Ser(Bzl)-OH.HCl
I-HL-Ser(Bzl)-OH I-HL-Ser(Bzl)-OL.HCl I-HL-Ser-OBzl.HCl
I-HL-Ser-OBzl I-DL-Ser-Obzl.Hcl I-D-Ser-Obzl.Hcl
I-HL-Ser(Bzl)-OMe·HCl I-Boc-L-Ser-OH I-Boc-L-Ser.H2O
I-Boc-DL-Ser-OH I-Boc-D-Ser-OH I-Boc-L-ser(mina)-OH
Boc-L-ser(mina).DCHA I-Boc-DL-Ser(mina)-OH I-Boc-D-ser(mina)-OH
I-Boc-L-Ser(tBu)-OH I-Boc-D-Ser(tBu)-OH I-Boc-D-Ser(Tbu).DCHA
I-Boc-L-Ser(Bzl)-OH I-Boc-DL-Ser(Bzl)-OH I-Boc-D-Ser(Bzl)-OH
I-Boc-Ser(Bzl)-ol I-Boc-D-Ser(Bzl)-OL I-Boc-L-Ser-OMe
I-Boc-DL-Ser-Ome I-Boc-D-Ser-OMe I-Boc-D-Ser-Oet
I-Boc-L-Ser-Obzl I-Boc-D-Ser-Obzl I-Boc-L-Ser (bzl)-OSu
I-Fmoc-L-Ser(bzl)-OH I-Fmoc-D-Ser(bzl)-OH I-Fmoc-L-Ser-Obzl
I-Fmoc-N-Me-Ser(bzl) I-ZL-Ser(Bzl)-OH I-Cbz-D-Ser(Bzl)-OH
I-Cbz-L-Ser-Obzl  

Kungani Khetha Thina

1. Mayelana Nentengo: Intengo iyaxoxisana.Singayilungisa ngokuya ngobuningi bakho.
2. Mayelana ne-OEM: Ungathumela umklamo wakho kanye nelogo.Singavula isikhunta esisha kanye nelogo, bese sithumela isampula ukuze siqinisekiswe.
3. Mayelana nokushintshisana: Ngicela ungithumele i-imeyili noma ungixoxele ngesikhathi esivumelana nawe.
4. Ikhwalithi ephezulu: Ukusetshenziswa kwezinto ezisezingeni eliphezulu, ukusungulwa kwesistimu yokulawula ikhwalithi eqinile, abasebenzi abaqokiwe abanomthwalo wemfanelo kuyo yonke inqubo yokukhiqiza kusukela ekuthengeni impahla eluhlaza kuya ekupakishweni.


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