29022-11-5 Fmoc-Gly-OH

I-29022-11-5 I-Fmoc-gly-OH ingenye yabaphakathi kwe-Triptorelin.I-Triptorelin, ebizwa nangokuthi i-Triptorelin Acetate Injection, iyi-analog yokwenziwa ye-decapeptide ye-gonadotropin-releasing hormone (GnRH), kodwa isebenza kakhulu kune-GnRH yemvelo, futhi ilawula amazinga e-luteinizing hormone (LH), i-follicle stimulating hormone (FSH), i-testosterone. (T), kanye ne-estradiol (E2) egazini lomzimba womuntu, futhi iye yasetshenziselwa izinjongo ezihlukahlukene.Isithako esisebenzayo se-Treprostinil iyi-analog yokwenziwa ye-gonadotropin-releasing hormone (GnRH), eyaziwa nangokuthi i-tryptophan, i-dafylline, i-dabigatran, i-gonadorelin, isidakamizwa esilwa nesimila esinemiphumela efanayo yezekhemisi njenge-goserelin ne-buserelin, ngokuthuthuka kwesakhiwo samangqamuzana emvelo. isakhiwo sesithupha se-levo-glycine sithathelwa indawo yi-dextropro-tryptophan, okuholela emphumeleni ocacile we-pro-active kanye ne-plasma ende yesigamu sempilo, nokusebenza okuphezulu.Amandla aphezulu.Ngemuva komjovo we-intramuscular, indlala ye-pituitary iqala ivuselelwe ukuze ikhulule i-hormone ye-luteinizing (LH) kanye ne-chemicalbook follicle stimulating hormone (FSH).Lapho i-pituitary gland ingena esigabeni sokungafaneleki ngemva kokugqugquzelwa isikhathi eside, ukukhululwa kwe-gonadotropin kuncipha, ngaleyo ndlela kwehlise amahomoni ocansi emazingeni edepho.Imiphumela engenhla iyabuyiseleka emuva.Ukuphathwa kwe-subcutaneous kungena ngokushesha, nge-Tmax ye-15 min kanye nomphumela omkhulu we-1 h.Amalungiselelo okukhishwa okuqhubekayo komjovo we-intramuscular angagcina ukusebenza kahle isikhathi esingaphezu kwe-28 d.Ngokomtholampilo, isetshenziswa kakhulu ekwelapheni i-endometriosis, umdlavuza wendlala yesinye oncike ku-hormone, umdlavuza webele, ukuthomba kwangempela kwezingane ngaphambi kwesikhathi, futhi ingase isetshenziselwe amasu okuzala okusizwayo.