3060-46-6 N-Me-L-Leu

I-Peptide Synthesis and Modification: I-N-Me-L-Leu ingasetshenziswa njengebhlokhi yokwakha ekuhlanganiseni kwe-peptide yesigaba esiqinile.Ivumela ukwethulwa kweqembu le-methyl endaweni ye-nitrogen ye-leucine, engashintsha izakhiwo ze-physicochemical kanye nomsebenzi we-biological we-peptide ewumphumela.Lokhu kuguqulwa kungathuthukisa ukuzinza kwe-peptide, kuguqule ukusebenzisana kwayo namanye ama-molecule, noma kube nomthelela ekuqondisweni kwayo kwamaselula.

Ucwaningo Lweproteomics: Ocwaningweni lwe-proteomics, i-N-Me-L-Leu ingasetshenziswa njengesisebenzi esilebula ubuningi bamaprotheni noma njengophenyo ukuze kuphenywe ukusebenzisana kwamaprotheni namaprotheni.Iqembu le-methyl lingahlinzeka ngethegi enkulu eyingqayizivele engatholwa nge-mass spectrometry, okuvumela ukuhlaziywa kwenani lamaphrotheni kuzingxube eziyinkimbinkimbi.

Ukutholwa Nokuthuthukiswa Kwezidakamizwa: I-N-Me-L-Leu inezinhlelo zokusebenza ezingaba khona ekutholakaleni nasekuthuthukisweni kwezidakamizwa.Ingafakwa kumakhandidethi ezidakamizwa ukuze kulungiswe umsebenzi wabo webhayoloji, ukuncibilika, noma izakhiwo zekhemisi.Iqembu le-methyl lingathinta ukuhambisana okubophezelayo komuthi ekuhlosweni kwawo, kuthuthukise ukungeneka kwamangqamuzana awo, noma kuguqule ukuqina kwawo kwe-metabolic.

I-Biological Probes and Imaging Agents: I-N-Me-L-Leu ingahlanganiswa nodayi be-fluorescent, ama-radiolabel, noma amanye ama-molecule entatheli ukuze kwakhe ama-biological probes noma ama-imaging agents.Lawa ma-probe angasetshenziselwa ukubona ngeso lengqondo noma ukulinganisa izinqubo ezithile zebhayoloji kumaseli noma izicubu, anikeze imininingwane ngemisebenzi yamaselula kanye nezindlela zezifo.

Izithasiselo Zokudla Okunomsoco: Emkhakheni wokudla okunomsoco, i-N-Me-L-Leu ingase ibe namandla njengesengezo sokudla okunempilo noma isithako ekudleni okusebenzayo.I-Leucine iyi-amino acid ebalulekile ehilelekile ekuhlanganiseni amaprotheni kanye ne-metabolism yemisipha.Okuphuma kokunye kwe-methylated kungase kunikeze izinzuzo ezithile ezihlobene nokuthuthukisiwe kwe-bioavailability noma imiphumela eguquliwe ye-metabolic.