30992-29-1 I-Boc-L-Aib-OH ingaba ngomunye wabamaphakathi be-Anamorelin.
1. Ukwesekwa kokudla okunomsoco kanye nokukhuthaza ukudla (indima ye-Anamorelin)
Njengomuthi omusha wokwelapha i-cachexia yomdlavuza, i-Anamorelin ingakhuthaza iziguli ukuthi zidle izakhi eziningi ngokuvuselela isifiso sokudla.Iziguli ezinomdlavuza i-cachexia ngokuvamile zinenkinga yokungathandi ukudla, i-anorexia nokukhathala, okuholela ekwehleni kwesisindo nokungondleki kahle.I-Anamorelin ikhulisa ukudla ngokushintshanisa ukukhululwa kwamahomoni esifiso sokudla kanye nokwenza ngcono ukuqashelwa kwesiguli nokusabela kokudla.Ngokwenza ngcono ukudla okunomsoco, i-Anamorelin isiza ukuthuthukisa isimo somzimba wesiguli nokwandisa ukumelana nezifo.
2. Ukuvikelwa kwemisipha kanye nokululama kokusebenza
Iziguli ezine-cachexia zivame ukuhlotshaniswa nokulahlekelwa kwemisipha nokunciphisa ukusebenza komzimba.I-Anamorelin ivikela futhi ikhulise imisipha ye-muscle ngokuthuthukisa ukusebenza kahle kwe-protein metabolism, ikhulise ibhalansi ye-protein synthesis kanye nokuwohloka, nokunciphisa i-muscle catabolism ngenkathi ikhuthaza ukudla.Ngaphezu kwalokho, i-Anamorelin ithuthukisa ukukhathala nokuqina, isiza iziguli ezine-cachexia ukuthi ziphinde ziphinde zivuselele amandla nokusebenza.
3. Ukuthuthukiswa kwesimo somqondo kanye nezinga lempilo
I-Cancer cachexia ayithinti nje kuphela impilo yomzimba yeziguli, kodwa futhi ithinta kakhulu isimo sazo sengqondo kanye nezinga lempilo yazo.Umphumela wokwelapha we-Anamorelin awugcini nje kuphela esicini somzimba, ungase futhi uthuthukise imizwelo nemizwa yesiguli ngokuthuthukisa isimo sengqondo.Ucwaningo luye lwabonisa ukuthi iziguli ezisebenzisa i-Anamorelin zinentuthuko enkulu esimweni sengqondo, ukusebenza komphakathi, ukukhathala nokwaneliseka kokuphila.Ithuthukisa kakhulu izinga lempilo yeziguli futhi ikhulise ukuzethemba kwazo ekulweni nomdlavuza.
4. Umphumela wokwelashwa ophelele kanye nokuthuthukiswa kokuvuselela
I-Anamorelin inendima ebalulekile ekwelapheni okudidiyelwe phakathi kweziguli ezinomdlavuza ezinesifo esiyingozi.Ingahlanganiswa nezinye izidakamizwa, i-chemotherapy, i-radiotherapy nezinye izindlela zokwelapha ukwenza umphumela ophelele.Ngokuthuthukisa isimo somsoco wesiguli, isisindo semisipha kanye nesimo sengqondo, i-Anamorelin ingathuthukisa umphumela wokwelapha jikelele.Iziguli ezine-cachexia nazo zingazuza ohlelweni lokuvuselela.