isibhengezo_sekhasi

33208-99-0 L-Ala-NH2.HCl

33208-99-0 L-Ala-NH2.HCl

Incazelo emfushane:

Ukubukeka Impushana emhlophe
MF I-C3H9ClN2O
MW 124.57
Ubumsulwa 98+


Imininingwane Yomkhiqizo

Isimo sezokuthutha
Kungaba kuzinga lokushisa elijwayelekile

Ncoma indlela yokuthumela
Ngomoya Ngomhlaba Ngasolwandle

Isimo sesitoreji:
Gcina endaweni emnyama, emkhathini ongangeni, izinga lokushisa legumbi

Impilo yeshelufu
Cishe iminyaka emi-2

Ubuncane be-oda Ubuningi:
1kg (ingxoxo)

Isitifiketi:I-COA, indawo encibilikayo, i-SpecificRotation [α]D20                      

Sizothumela noma iyiphi idatha oyifunayo.Ungabona idatha ngaphambili njengereferensi.

Ngemikhiqizo eyenziwe ngokwezifiso, sithumela idatha entsha kakhulu ngemuva kokuthi iphumile.

I-D-Ls(tfa)-NCA (2)

Omqondofana

I-L-ALANAMINE HCL;

(L) -ALANINAMIDE HCL;

L-Ala-NH2·HCl;

(S)-2-AMINOPROPIONAMIDE HYDROCHLORIDE;

H-Ala-NH2·HCl (HPLC);

L-ALANINAMIDE HYDROCHLORIDE;

L-ALANINE AMIDE HYDROCHLORIDE;

ALANINE-NH2 HCL

Ukupakisha kwangaphakathi

Zivame ukusetshenziselwa ukupakisha impushana.Kuya ngemfuneko yamakhasimende.Ngakho-ke, sitshele ngenkani yakho ngaphambi kokupakisha uma unezicelo ezikhethekile.

Ukupakisha kwangaphakathi 2
Ukupakisha kwangaphakathi 1
Ukupakisha kwangaphakathi 3

ukupakisha kwangaphandle

1kg kuya ku-25kg Ukupakisha kwangaphandle kunzima.Futhi kunzima ukusika nokulimaza.Ingavikela imikhiqizo yakho ngokuphelele.

Ukupakisha kwangaphandle 3
Ukupakisha kwangaphandle 2
Ukupakisha kwangaphandle 1

Izinhlelo zokusebenza

I-L-Alaninamidehydrochloride, eyaziwa nangokuthi (S) -2-aminopate hydrochloride, nayo iyikristalu emhlophe.I-Chemicalbook yayo incibilika kalula emanzini futhi incibilike ku-ethanol.I-Inserthol ayincibiliki.Ingasetshenziswa njenge-organic synthetic intermediate ne-pharmaceutical intermediate, esetshenziswa kakhulu ocwaningweni lwaselabhorethri nenqubo yokuthuthukiswa kanye nenqubo yokukhiqiza imithi yamakhemikhali.

Kuyi-intermediate yemithi ye-safinamide.Lo mkhiqizo unezinqubo ezihlukahlukene, ezingakwazi kuphela ukukhetha kakhulu futhi zihlehliswe ukuvimbela i-monoamine oxidase B (MAO-B), kodwa futhi ivimbele ukutholwa kabusha kwe-dopamine, vimba iziteshi ze-sodium ezincike ukuncika kwamandla kagesi, lawula iziteshi ze-calcium, ngaleyo ndlela kucindezela i-glutamic aminamida.Ukukhishwa kwe-Acid.Isimiso sezinzwa esimaphakathi salo mkhiqizo siphezulu.Imitholampilo ibonisa ukuthi lesi sidakamizwa singathuthukisa ukuzivocavoca nokusebenza kwengqondo kweziguli zika-Parkinson, kuvimbele iziguli ekuthuthukiseni i-dyskinesia, futhi zibe nokubekezelelana okuhle.

imikhiqizo ehlobene

L-ALA DL-ALA I-L-Ala-NCA
H-Ala-ol β-Ala-ol I-D-Ala-NCA
D-ALA H-β-Ala-OH HN-Me-D-Ala-OH
L-Ala-nbu.hcl I-D-ALA-Oipr.HCL I-HD-Ala-OBzl·HCl
I-HD-Ala-Oet.HCl I-HL-ALA-Oipr.HCL N-Me-Ala-Otbu.Hcl
HL-Ala-OtBu·HCl H-DL-Ala-OMe.HCl I-HD-Ala-NH2·HCl
I-HD-Ala-NH2 I-Ac-L-Ala-NH2 I-Ac-D-Ala-NH2
I-Boc-Ala-NH2 I-Boc-D-Ala-NH2 I-Boc-β-Ala-NH2
fmoc-β-Ala-NH2  

Ukuphakama

1. Hlangana nezidingo zakho ezenziwe ngokwezifiso.
2. Nikeza izinga okusezingeni eliphezulu amp;intengo izoncintisana kakhulu.
3. Isevisi enhle kakhulu yangemva kokuthengisa.
4. Uhlu lwemibuzo yabahlinzeki kanye nemibhalo yezobuchwepheshe inganikezwa uma inani elithile lama-oda lifinyelelwa.
5. Isevisi enhle yangemuva kokuthengisa noma isiqinisekiso: sizophendula ngokushesha kakhulu kunoma imiphi imibuzo yakho.
6. Thumela imikhiqizo encintisanayo kanye nokuthekelisa emazweni angaphandle ngobuningi njalo ngonyaka.
7. Nikeza amasampula mahhala ukuze uhlole ikhwalithi ngaphambi kokukhokha.


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