isibhengezo_sekhasi

340-90-9 N-Pht-Glu

340-90-9 N-Pht-Glu

Incazelo emfushane:

Ukubukeka Impushana emhlophe ukuya kokumhlophe
MF I-C13H11NO6
MW 277.23
Ubumsulwa 98+


Imininingwane Yomkhiqizo

Isimo sezokuthutha
Kungaba kuzinga lokushisa elijwayelekile

Ncoma indlela yokuthumela
Ngomoya Ngomhlaba Ngasolwandle

Isimo sesitoreji:
Gcina endaweni emnyama, emkhathini ongangeni, izinga lokushisa legumbi

Impilo yeshelufu
Cishe iminyaka emi-2

Ubuncane be-oda Ubuningi:
1kg (ingxoxo)

Isitifiketi:I-COA, indawo encibilikayo, i-SpecificRotation [α]D20                      

Sizothumela noma iyiphi idatha oyifunayo.Ungabona idatha ngaphambili njengereferensi.

Ngemikhiqizo eyenziwe ngokwezifiso, sithumela idatha entsha kakhulu ngemuva kokuthi iphumile.

I-D-Ls(tfa)-NCA (2)

Omqondofana

(2S)-2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)pentanedioicacid;

i-n-phthalyl-l-glutamicacid;

I-N-PHTHALIMIDEL-GLUTAMINCACID;

I-N-PHTHALOYL-L-GLUTAMICACID;

I-PHTHALYL-L-GLUTAMICACID;

I-PHTHALOYL-L-GLUTAMICACID;

I-PHT-GLU-OH;

I-PHGA

Ukupakisha kwangaphakathi

Zivame ukusetshenziselwa ukupakisha impushana.Kuya ngemfuneko yamakhasimende.Ngakho-ke, sitshele ngenkani yakho ngaphambi kokupakisha uma unezicelo ezikhethekile.

Ukupakisha kwangaphakathi 2
Ukupakisha kwangaphakathi 1
Ukupakisha kwangaphakathi 3

ukupakisha kwangaphandle

1kg kuya ku-25kg Ukupakisha kwangaphandle kunzima.Futhi kunzima ukusika nokulimaza.Ingavikela imikhiqizo yakho ngokuphelele.

Ukupakisha kwangaphandle 3
Ukupakisha kwangaphandle 2
Ukupakisha kwangaphandle 1

Izinhlelo zokusebenza

I-PHTHALYL-L-GLUTAMIC ACID ingasetshenziswa ukwenza (R)-(+)-THALIDOMIDE.Iphuma ku-glutamic acid engenawo umphumela wokwelapha ochokweni, futhi isetshenziswa kanye nemithi elwa nochoko ukunciphisa ukusabela kochoko kanye nokwelapha izinhlobo ezihlukahlukene zokusabela kochoko, njengama-lymph nodes akhulisiwe, i-erythema nodosum, imfiva, i-arthralgia ne-neuralgia ngendlela ephumelelayo. .
Imiphumela ye-thalidomide ye-immunomodulatory yahlukahluka kakhulu kuye ngezimo zokuhlola, nemiphumela kwesinye isikhathi engqubuzanayo.Imithelela kuma-lymphocyte ihlanganisa ukuncipha kwamaseli e-CD4+ kanye nokukhuthazwa kwamaseli e-CD8+, okuholela ekwehleni kwesilinganiso se-CD48.
Ukwengeza, i-thalidomide ibonakala yenza ushintsho lusuka ku-Th1 luye empendulweni ye-Th2.
I-Cyclosporine ne-thalidomide esebenza kuma-subtypes amabili we-T lymphocytes, i-Th1 ne-Th2, ne-Thd itholakale ikhuthaza futhi ithuthukise ukuhlanganiswa kwe-IL-4 ne-IL-5, ivimbela ukuhlanganiswa kwe-interferon gamma (IFN-γ) nge-phytohemagglutinin-stimulated human. i-peripheral blood monocytes, nokunciphisa amazinga e-TNF-α, IL-6, kanye ne-IL-10 mRNAs, ngaphandle komphumela kumazinga we-IL-12 kanye ne-IFN-γ mRNA ayengenawo umthelela.

imikhiqizo ehlobene

HL-Glu-OH I-HD-Glu-OH I-DL-Glu-OH I-Boc-L-Glu-OH
I-Boc-D-Glu-OH I-Boc-Glu (trt)-OH I-Fmoc-L-Glu-OH I-Fmoc-D-Glu-OH
Cbz-L-Glu-OH Cbz-D-Glu-OH I-Cbz-L-Glu-Otbu I-Cbz-L-Glu(Oet)-OH

Kungani Khetha Thina

1. Mayelana ne-MOQ: Singayilungisa ngokuvumelana nemfuneko yakho.
2. Mayelana nesampula: Isampula idinga imali yesampula, okungaba yimpahla ongayilanda noma ongasikhokhela kusengaphambili.
3. I-Mold workshop, ingenziwa ngezifiso ngokusho kwenani lamamodeli.
4. Sinikeza isevisi engcono kakhulu.Ithimba labadayisi abanolwazi selisebenzela wena.
5. Mayelana nokushintshisana: Ngicela ungithumele i-imeyili noma ungixoxele ngesikhathi esivumelana nawe.


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