isibhengezo_sekhasi

53978-73-7 Cbz-N-Me-D-Val-OH

53978-73-7 Cbz-N-Me-D-Val-OH

Incazelo emfushane:

Ukubukeka Impushana emhlophe ukuya kokumhlophe
MF I-C14H19NO4
MW 265.3
Ubumsulwa 98+


Imininingwane Yomkhiqizo

Isimo sezokuthutha
Kungaba kuzinga lokushisa elijwayelekile

Ncoma indlela yokuthumela
Ngomoya Ngomhlaba Ngasolwandle

Isimo sesitoreji:
Gcina endaweni emnyama, emkhathini ongangeni, izinga lokushisa legumbi

impilo yeshelufu
Cishe iminyaka emi-2

Ubuncane be-oda Ubuningi:
1kg (ingxoxo)

Isitifiketi:I-COA, indawo encibilikayo, i-SpecificRotation [α]D20                      

Sizothumela noma iyiphi idatha oyifunayo.Ungabona idatha ngaphambili njengereferensi.

Ngemikhiqizo eyenziwe ngokwezifiso, sithumela idatha entsha kakhulu ngemuva kokuthi iphumile.

I-D-Ls(tfa)-NCA (2)

Omqondofana

(R) -2-((benzyloxycarbonyl)(methyl)amino)-3-methylbutanoicacid;

Cbz-N-Methyl-D-Valine;

N-Methyl-N-Cbz-D-valine;

N-Methyl-N-[(phenylmethoxy)carbonyl]-D-valine;

I-N-Benzyloxycarbonyl-N-methyl-D-valine;

Cbz-N-Me-D-Val-OH;

(2R)-2-{[(benzyloxy)carbonyl](methyl)amino}-3-methylbutanoicacid;

I-N-Cbz-N-methyl-D-valine

Ukupakisha kwangaphakathi

Zivame ukusetshenziselwa ukupakisha impushana.Kuya ngemfuneko yamakhasimende.Ngakho-ke, sitshele ngenkani yakho ngaphambi kokupakisha uma unezicelo ezikhethekile.

Ukupakisha kwangaphakathi 2
Ukupakisha kwangaphakathi 1
Ukupakisha kwangaphakathi 3

ukupakisha kwangaphandle

1kg kuya ku-25kg Ukupakisha kwangaphandle kunzima.Futhi kunzima ukusika nokulimaza.Ingavikela imikhiqizo yakho ngokuphelele.

Ukupakisha kwangaphandle 3
Ukupakisha kwangaphandle 2
Ukupakisha kwangaphandle 1

Izinhlelo zokusebenza

I-Peptide Synthesis: I-Cbz-N-Me-D-Val-OH isebenza njengebhlokhi yokwakha ebalulekile ekuhlanganiseni kwe-peptide yesigaba esiqinile.Iqembu layo elivikelayo le-benzoyl (Cbz) liqinisekisa ukuzinza phakathi nenqubo yokuhlanganisa, kuyilapho i-N-methylation ithuthukisa ukunyibilika nokusebenza kabusha.Lokhu kuvumela ukwethulwa okuphumelelayo kwezinsalela ze-D-valine kumaketanga e-peptide, okuholela kuma-peptide ahlanzekile anemisebenzi yebhayoloji efiselekayo.

Izifundo Zebhayoloji: Ama-Peptides adlala indima ebalulekile ezinqubweni ezihlukahlukene zebhayoloji, njengokudluliswa kwesignali, ukulawulwa kwama-enzyme, nokusabela komzimba.Ukutholakala kwe-Cbz-N-Me-D-Val-OH kuvumela abacwaningi ukuthi bahlanganise ama-peptide aqukethe izinsalela ze-D-valine, okubenza bakwazi ukuphenya izindima ezithile nokusebenzisana kwalawa ma-peptide ezinhlelweni zebhayoloji.

Ukutholwa Nokuthuthukiswa Kwezidakamizwa: Izidakamizwa ezisekelwe ku-Peptide zithole ukunakwa okukhulu eminyakeni yamuva nje ngenxa yokucaciswa kwazo okuphezulu kanye nobuthi obuphansi.I-Cbz-N-Me-D-Val-OH, njengengxenye ebalulekile ekuhlanganiseni kwe-peptide, ingasetshenziswa ekwakhiweni nasekuthuthukisweni kwemithi ye-peptide inoveli.Ngokuhlanganisa izinsalela ze-D-valine kule mithi, abacwaningi bangakwazi ukudala izindlela zokwelapha ezisebenza kahle kakhulu ezinezici zebhayoloji ezihlukile.

imikhiqizo ehlobene

L-Val-OH I-DL-Val I-HD-Val-OH N-Me-L-Val-OH
I-N-Me-L-Val.HCl I-N-Me-D-Val N-Me-D-Val-OH·HCl N-Me-L-Val-Ome.HCl
N-Me-D-Val-Ome.HCl I-N-Me-Val-Obzl.HCl I-N-Me-D-Val-Obzl.HCl I-N-Me-Val-Obzl.Tos
I-Boc-N-Me-Val-OH I-Boc-N-Me-D-Val-OH I-Fmoc-N-Me-Val-OH I-Fmoc-N-Me-DL-Val-OH
I-Fmoc-N-Me-D-Val-OH Cbz-N-Me-L-Val-OH  

Kungani Khetha Thina

1. Mayelana ne-MOQ: Singayilungisa ngokuvumelana nemfuneko yakho.
2. Mayelana nesampula: Isampula idinga imali yesampula, okungaba yimpahla ongayilanda noma ongayikhokha kithi kusengaphambili.
3. I-Mold workshop, ingenziwa ngezifiso ngokusho kwenani lamamodeli.
4. Sinikeza isevisi engcono kakhulu.Ithimba labadayisi abanolwazi selisebenzela wena.
5. Mayelana nokushintshisana: Ngicela ungithumele i-imeyili noma ungixoxele ngesikhathi esivumelana nawe.


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