I-China 583840-03-3 SORAFENIB N-OXIDE Umkhiqizi kanye Nemboni |Jiayinglai

583840-03-3 SORAFENIB N-OXIDE

Incazelo emfushane:

Ukubukeka	Okuqinile okumhlophe
MF	I-C21H16ClF3N4O4
MW	480.82
Ubumsulwa	98+

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Isimo sezokuthutha&indlela yokuthumela enconyiwe:
ngomoya, ngolwandle noma nge-express

Isimo sesitoreji:
2-8°C

Ubuncane be-oda Ubuningi:
Ukuxoxisana

Isitifiketi:
I-COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC iyatholakala

Omqondofana

I-Sorafenibimpurity23/SorafenibN-Oxide/4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-2-(methylcarbamoyl)pyridine1-oxide;

I-SORAFENIBN-OXIDE;

4-[4-[[[4-Chloro-3-(trifluoroMethyl)phenyl]aMino]carbonyl]aMino]phenoxy]-N-Methyl-2-pyridinecarboxaMide1-Oxide;

I-SorafenibImpurity27(SorafenibN-Oxide);

I-2-Pyridinecarboxamide,4--[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-,1-oxide;

4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-2-(methylcarbamoyl)pyridine1-oxide;

Sorafenibimpurities172;

I-Sorafenibimpurities11

Ukupakisha kwangaphakathi

Ngokuvamile zisetshenziselwa ukupakisha impushana.Futhi zingavimbela ukukhanya kwelanga namanzi ukuba kungabi kubi.

ukupakisha kwangaphandle

Ibhokisi eliqinile lingavikela imikhiqizo yakho ukuthi ingaphahlazeka futhi ibe manzi.

Izinhlelo zokusebenza

Kukhemistri nesayensi yezinto zokwakha, ukungcola kuyizinto zamakhemikhali ngaphakathi kwenani elivalekile loketshezi, igesi, noma okuqinile, okuhlukile ekwakhekeni kwamakhemikhali wento noma inhlanganisela.Okokuqala, ikhemikhali emsulwa kufanele ivele ngokwe-thermodynamically okungenani esigabeni samakhemikhali esisodwa futhi ingabonakala ngomdwebo wayo wengxenye eyodwa.Okwesibili, uma sikhuluma nje, ikhemikhali emsulwa kufanele ibonakale ifana (okungukuthi, ngeke ikhombise ukuguqulwa kwezakhiwo ngemuva kokwenza izinqubo eziningi ezahlukene zamakhemikhali zokuhlaziya ezilandelanayo).Ikhemikhali ehlanzekile ephelele izodlula yonke imizamo kanye nokuhlolwa kokuhlukana okuqhubekayo nokuhlanzwa.Okwesithathu, futhi lapha sigxila encazelweni evamile yamakhemikhali, akufanele iqukathe noma yiluphi olunye uhlobo lwamakhemikhali.Eqinisweni, awekho ngokuphelele ama-chemical compounds ahlanzekile angu-100%, njengoba kuhlale kunokungcola okuthile.Ngempela, njengoba imingcele yokuthola kukhemikhali yokuhlaziya iyancipha, inani lokungcola elitholiwe livame ukwanda.

Ukungcola kuyenzeka ngokwemvelo noma kwengezwe ngesikhathi sokuhlanganiswa kwamakhemikhali noma umkhiqizo wokuhweba.Ngesikhathi sokukhiqiza, ukungcola kungase kwengezwe ngamabomu, ngengozi, ngokungenakugwenywa, noma kwenzeke ngephutha entweni.

Amazinga okungcola kokuthile ngokuvamile achazwa ngokwemibandela ehlobene.Amazinga asungulwe izinhlangano ezihlukahlukene ezizama ukuchaza amazinga avunyelwe okungcola okuhlukahlukene emkhiqizweni okhiqiziwe.Uma sikhuluma ngokuqinile, izinga lokuhlanzeka kwempahla lingashiwo nje njengokuhlanzeka okungaphezulu noma okuncane kunezinye izinto.

Ukuphakama

1. Isevisi ye-R&D iyatholakala
2. Umkhiqizi oqinisekisiwe we-ISO, isiqinisekiso sekhwalithi
I-3.Inkambo ephelele yenkonzo yokulandelela ngesikhathi sokukhiqiza
I-4.Izindleko eziphezulu
5.Imibhalo yesitifiketi sekhwalithi enikeziwe ngokwesicelo sekhasimende ngalinye
I-6.Isevisi enhle emva kokuthengisa, ukugcina ubuhlobo obuseduze nekhasimende
7.Insiza egcwele yokusiza ukwehlisa izindleko zokuthumela
8.Isampula yamahhala enikelwe ukuhlola ikhwalithi ngaphambi kwanoma iyiphi inkokhelo
9.Isikhathi sokukhokha okuxoxiswana ngaso
10.Amakhasimende e-Assit abhekana nezindaba zaseShayina