isibhengezo_sekhasi

73724-46-6 Fmoc-L-Ser-Obzl

73724-46-6 Fmoc-L-Ser-Obzl

Incazelo emfushane:

Ukubukeka Impushana emhlophe ukuya kokumhlophe
MF I-C25H23NO5
MW 417.45
Ubumsulwa 98+


Imininingwane Yomkhiqizo

Isimo sezokuthutha&indlela yokuthumela enconyiwe:
ngomoya, ngolwandle noma nge-express

Isimo sesitoreji:
2-8°C

Ubuncane be-oda Ubuningi:
Ukuxoxisana

Isitifiketi:
I-COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC iyatholakala

I-D-Ls(tfa)-NCA (2)

Omqondofana

N-ALPHA-FMOC-O-BENZYL-L-SERINE;

I-N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-BENZYL-L-SERINE;

I-N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-BENZYL-L-SERINE;

i-benzyl(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxypropanoate;

FMOC-L-SER(BZL)-OH;

I-FMOC-SERINE(BZL)-OH;

I-FMOC-(S)-2-AMINO-3-BENZYLOXYPROPIONICACID;

L-Serine,N-[(9H-fluoren-9-ylMethoxy)carbonyl]-,phenylMethylester

Ukupakisha kwangaphakathi

Ngokuvamile zisetshenziselwa ukupakisha impushana.Futhi zingavimbela ukukhanya kwelanga namanzi ukuba kungabi kubi.

Ukupakisha kwangaphakathi 2
Ukupakisha kwangaphakathi 1
Ukupakisha kwangaphakathi 3

ukupakisha kwangaphandle

Ibhokisi eliqinile lingavikela imikhiqizo yakho ukuthi ingaphahlazeka futhi ibe manzi.

Ukupakisha kwangaphandle 3
Ukupakisha kwangaphandle 2
Ukupakisha kwangaphandle 1

Izinhlelo zokusebenza

I-Ester yenziwe ngokusabela kwe-esterization ye-asidi ye-inorganic noma i-organic acid noma utshwala.Utshwala noma i-phenol noma i-anhydride ene-asidi, utshwala ne-ethylene, i-asidi yamahhala kanye nokuphuma kokuphuma kwe-nitrogen okunamafutha nakho kungakhiqiza i-ester.I-hydrogen eku-alpha-carbon kuma-molecule e-ester ilahlekelwa uphuzo oludakayo lwengqamuzana nenye i-ester yengqamuzana ngaphansi kwezimo ze-alkali ukuze ikhiqize i-β-keto ester, ebizwa ngokuthi i-ester contraction reaction.Isibonelo, i-acetyl acetate ikhiqizwa ukukhiqiza i-acetyl ethyl acetate.Lokhu kusabela kubaluleke kakhulu ku-organic synthesis.

Igama le-ester livela egameni elihambisanayo le-carboxylic acid notshwala noma i-phenol, njengokuthi "i-asidi ethile ne-ester ethile".I-Circle esters ibizwa ngokuthi i-lactone (lactone).Izici zamakhemikhali ze-ester zifana ne-amyl niche anhydride, ejwayele ukusabela kwe-hydrolysis, utshwala kanye ne-ammonia.I-ester yezinga eliphansi iwuketshezi olunephunga elimnandi futhi oluguquguqukayo olungenambala, futhi i-ester ethuthukisiwe iqinile.I-Estes izincibilikisi ezibalulekile nezinto zokwenziwa zokwenziwa, kanti amanye ama-ester ayizidakamizwa ngokwazo.Ngokohlobo lwe-asidi, i-ester ingahlukaniswa ibe i-asidi ye-inorganic ester ne-organic acid ester.I-Etate, i-ethyl acetate i-ester enamafutha, i-acetate i-ester enamakha, futhi i-namanonate i-ester eyi-cyclic.

I-ester ngokuvamile iwuketshezi olungenambala olungathathi hlangothi.I-ester ekhiqizwe umjaho wamafutha kanye notshwala obugcwele inephunga lesithelo, elingancibilika emanzini, futhi kunzima futhi ukuncibilika emanzini.Enye iphoyinti elikhanyayo le-ester liphansi futhi livame ukusha.Umusi ungamuncwa umgudu wokuphefumula, futhi i-ester ewuketshezi ingamuncwa isikhumba.Ngemva kokumuncwa, iyancibilika ku-plasma, kanti ezinye zazo zikhishwa ngamaphaphu nezinso.Ngemuva kwe-hydrolysis ethile, phenduka ube yinqubo evamile ye-metabolic.Ngaphezu kwezinhlanganisela ezimbalwa ze-ester, eziningi zazo zinobuthi kakhulu futhi zinobuthi kakhulu, futhi eziningi zazo ziyi-micro-toxic kuya ezigabeni ezinobuthi obuphakathi, futhi eziningi zazo aziwona ubuthi.Kunama-ester angama-38 emaqenjini etiye.Ikakhulukazi: ① i-ester enamafutha: ekhiqizwa utshwala namafutha, njenge-ethyl acetate, i-hexyl hexyate.② I-ester enephunga elimnandi: ekhiqizwa utshwala ne-asidi enamakha, njenge-Shun-3-hexylzyl.③ I-Circin esters: ekhiqizwa utshwala ne-cyclocar, njenge-jasmone hyacxide.I-ester ngokuvamile ayithathi hlangothi, engenziwa i-hydrolyzed futhi ikhiqize utshwala ne-asidi.Izinombolo zekhabhoni ephansi ngokuvamile ziwuketshezi olunuka kamnandi, futhi izinombolo zekhabhoni ephezulu ziwuketshezi kanye nezinto eziqinile ezingancibiliki emanzini.

imikhiqizo ehlobene

I-Fmoc-L-Ser(bzl)-OH I-Fmoc-D-Ser(bzl)-OH I-Fmoc-N-Me-Ser(bzl) I-ZL-Ser(Bzl)-OH
I-Cbz-D-Ser(Bzl)-OH I-Cbz-L-Ser-Obzl I-Fmoc-Ser-Ome I-Fmoc-D-Ser-Ome
Fmoc-L-Ser(Mina)-OH I-Fmoc-Ser(Ac)-OH I-Fmoc-D-Ser(tBu)-OH I-Boc-L-Ser (bzl)-OSu

Ukuphakama

1. Isevisi ye-R&D iyatholakala
2. Umkhiqizi oqinisekisiwe we-ISO, isiqinisekiso sekhwalithi
I-3.Inkambo ephelele yenkonzo yokulandelela ngesikhathi sokukhiqiza
I-4.Izindleko eziphezulu
5.Imibhalo yesitifiketi sekhwalithi enikeziwe ngokwesicelo sekhasimende ngalinye
I-6.Isevisi enhle emva kokuthengisa, ukugcina ubuhlobo obuseduze nekhasimende
7.Insiza egcwele yokusiza ukwehlisa izindleko zokuthumela
8.Isampula yamahhala enikelwe ukuhlola ikhwalithi ngaphambi kwanoma iyiphi inkokhelo
9.Isikhathi sokukhokha okuxoxiswana ngaso
10.Amakhasimende e-Assit abhekana nezindaba zaseShayina


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