isibhengezo_sekhasi

U-Boc-Wakhe(Boc)-Aib-OH

U-Boc-Wakhe(Boc)-Aib-OH

Incazelo emfushane:

Ukubukeka Impushana emhlophe ukuya kokumhlophe
MF
MW
Ubumsulwa 98+


Imininingwane Yomkhiqizo

Isimo sezokuthutha
Kungaba kuzinga lokushisa elijwayelekile

Ncoma indlela yokuthumela
Ngomoya Ngomhlaba Ngasolwandle

Isimo sesitoreji:
Gcina endaweni emnyama, emkhathini ongangeni, izinga lokushisa legumbi

impilo yeshelufu
Cishe iminyaka emi-2

Ubuncane be-oda Ubuningi:
1kg (ingxoxo)

Isitifiketi:I-COA, indawo encibilikayo, i-SpecificRotation [α]D20                      

Sizothumela noma iyiphi idatha oyifunayo.Ungabona idatha ngaphambili njengereferensi.

Ngemikhiqizo eyenziwe ngokwezifiso, sithumela idatha entsha kakhulu ngemuva kokuthi iphumile.

I-D-Ls(tfa)-NCA (2)

Omqondofana

U-Boc-Wakhe(Boc)-Aib-OH

Ukupakisha kwangaphakathi

Zivame ukusetshenziselwa ukupakisha impushana.Kuya ngemfuneko yamakhasimende.Ngakho-ke, sitshele ngenkani yakho ngaphambi kokupakisha uma unezicelo ezikhethekile.

Ukupakisha kwangaphakathi 2
Ukupakisha kwangaphakathi 1
Ukupakisha kwangaphakathi 3

ukupakisha kwangaphandle

1kg kuya ku-25kg Ukupakisha kwangaphandle kunzima.Futhi kunzima ukusika nokulimaza.Ingavikela imikhiqizo yakho ngokuphelele.

Ukupakisha kwangaphandle 3
Ukupakisha kwangaphandle 2
Ukupakisha kwangaphandle 1

Izinhlelo zokusebenza

I-Peptide Synthesis and Modification:I-Boc-His(Boc)-Aib-OH ingasebenza njengebhlokhi yokwakha ngaphakathi kweketango le-peptide, evumela ukwakhiwa kwama-peptide ngokulandelana okukhethekile nemisebenzi ngokuxhunyaniswa namanye ama-amino acid noma izingxenye ze-peptide.Lawa ma-peptide ahlanganiswe ngokwezifiso anokusebenza okubanzi ekutholweni kwezidakamizwa, ucwaningo lwe-biochemical, nezinye izindawo ezihlobene.
Uma kubhekwa ubukhona be-histidine (Yakhe) kanye ne-α-aminoisobutyric acid (Aib), izici eziyingqayizivele zalawa ma-amino acid zenza i-Boc-His(Boc)-Aib-OH ibe nendima ebalulekile ekulandeleni okuthile kwe-peptide.Bangathuthukisa ukuzinza kanye nomsebenzi webhayoloji wama-peptide.
I-Biological Activity Research and Regulation:I-Boc-His(Boc)-Aib-OH inomsebenzi wemvelo webhayoloji, okuyenza ibe ithuluzi elibalulekile lezifundo zomsebenzi webhayoloji.Abacwaningi bangakwazi ukuyethula ezinhlelweni zebhayoloji ukuze babone umthelela wayo ezinqubweni zamaselula, ngaleyo ndlela bathole ulwazi olujulile mayelana nezinqubo ze-physiological and pathological.
Ngokuxhaphaza iqembu le-imidazole le-histidine kanye nesakhiwo esiyingqayizivele se-α-aminoisobutyric acid, i-Boc-His(Boc) -Aib-OH ingathonya ukusebenzisana kwayo nama-receptors noma amanye ama-biomolecules, ilawula izimpendulo ezithile zezinto eziphilayo noma izindlela zokudlulisa isignali.
Ukwakhiwa Nokuthuthukiswa Kwezidakamizwa:I-Boc-His(Boc)-Aib-OH iphethe inani elingase libe khona lesicelo emkhakheni wokutholwa kwezidakamizwa.Ukuguqulwa kwesakhiwo noma ukulungiselelwa kungaholela ekuhlanganisweni nemisebenzi ethile yezemithi, esebenza njengemithi yabantu ukuze kuphenywe futhi kuthuthukiswe.
Uma kucatshangelwa izici ezingaba khona zokuhlambulula i-ion yensimbi yeqembu le-imidazole le-histidine kanye ne-biocompatibility ye-α-aminoisobutyric acid, i-Boc-His(Boc)-Aib-OH ingase yakhelwe ukuthuthukiswa kwezidakamizwa okuqondiswe ezifweni ezithile noma okuhlosiwe kwebhayoloji.
Ucwaningo lwe-Biochemical and Biophysical:I-Boc-His(Boc)-Aib-OH ingasebenza njengenhlanganisela yemodeli yokutadisha izindlela zokusebenzisana phakathi kwama-peptide nama-biomolecules afana namaprotheni ne-DNA, kanye nokugoqa kwe-peptide nokuzinza ngaphakathi kwezinhlelo zebhayoloji.

Ngophenyo ekusebenzisaneni kwayo nama-biomolecules ahlukahlukene, ukuqonda okujulile kwezakhiwo ze-biochemical nemisebenzi yama-peptide kungazuzwa.

imikhiqizo ehlobene

L-His-OH I-HD-His-OH H-His(trt)-OH Boc-L-His(Boc)-OH.Dcha
U-Boc-Wakhe(Boc)-OH Boc-D-His(Boc)-OH Fmoc-D-His(Fmoc)-OH FMOC-Yakhe(BOC)-OH
Boc-L-His(Trt)-Aib-OH

Kungani Khetha Thina

1. Mayelana ne-MOQ: Singayilungisa ngokuvumelana nemfuneko yakho.
2. Mayelana nesampula: Isampula idinga imali yesampula, okungaba yimpahla ongayilanda noma ongayikhokha kithi kusengaphambili.
3. I-Mold workshop, ingenziwa ngezifiso ngokusho kwenani lamamodeli.
4. Sinikeza isevisi engcono kakhulu.Ithimba labadayisi abanolwazi selisebenzela wena.
5. Mayelana nokushintshisana: Ngicela ungithumele i-imeyili noma ungixoxele ngesikhathi esivumelana nawe.


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