I-Fmoc-N-Me-D-Phg-OH, eyaziwa nangokuthi i-Fmoc-protected derivative ye-N-methyl-D-phenylglycine, iyinhlanganisela ebalulekile emikhakheni efana ne-biochemistry, i-peptide synthesis, kanye nokutholakala kwezidakamizwa.
I-Peptide Synthesis kanye ne-Solid-Phase Peptide Synthesis:
I-Fmoc-N-Me-D-Phg-OH idlala indima ebalulekile ekuhlanganiseni kwe-peptide yesigaba esiqinile.Njenge-amino acid monomer kule nqubo, ixhuma namanye ama-amino acid ngeqembu layo lokuvikela i-N-terminal Fmoc.Ukuncibilika kwamanzi kweqembu le-Fmoc kuvumela izinyathelo zokuhlanganisa kanye nokuvikela ukuthi zenziwe ngaphansi kwezimo ezithambile, kube lula ukuhlanganiswa okuphumelelayo kwamaketanga e-peptide.
Ukutholwa Kwezidakamizwa:
I-Fmoc-N-Me-D-Phg-OH ingasetshenziswa njengebhlokhi yokwakha ekuhlanganiseni ama-peptide namaphrotheni asebenza ngokwebhayoloji.Ngokuyihlanganisa namanye ama-amino acid, ama-peptide noma amaprotheni anezigcawu ezithile nemisebenzi ingahlanganiswa, engabonisa amandla okwelapha, njengama-enzyme inhibitors, ama-receptor antagonists, noma ama-immunomodulators.
Ucwaningo lwe-Biochemical:
Ocwaningweni lwamakhemikhali ezinto eziphilayo, i-Fmoc-N-Me-D-Phg-OH ingasetshenziswa ukuze kuhlanganiswe ama-peptide anelebuli noma amaprotheni ocwaningo olufana nokusebenzisana kwamaprotheni namaprotheni, i-enzyme kinetics, kanye nokwenza kwasendaweni kwamaselula.Ukwethulwa kwayo emaketangeni e-peptide kuvumela ukulandelela okulula nokutholwa kwe-peptide noma ukuziphatha nokusebenza kwamaprotheni.
I-Biological Probes kanye nama-ejenti wokuxilonga:
I-Fmoc-N-Me-D-Phg-OH futhi ingasetshenziswa ekuhlanganiseni ama-biological probes nama-ejenti okuxilonga.Ngenxa yokwakheka kwayo kwamakhemikhali athile kanye nokuguquguquka, ingasetshenziswa ukulebula ama-molecule ebhayoloji njengamasosha omzimba, ama-enzyme, noma ama-nucleic acid ukuze kusetshenziswe ekuxilongweni kwesifo, ukuthwebula isithombe sebhayoloji, noma ukuhlolwa kwezidakamizwa.