isibhengezo_sekhasi

1118767-15-9 Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OSu

1118767-15-9 Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OSu

Incazelo emfushane:

Ukubukeka Impushana emhlophe ukuya kokumhlophe
MF I-C47H82N4O15
MW 943.17
Ubumsulwa 98+


Imininingwane Yomkhiqizo

Isimo sezokuthutha
Ingathuthwa ngezinga lokushisa elivamile.

Ncoma indlela yokuthumela
ngomoya, ngomhlaba noma ngolwandle

Isimo sesitoreji:
2-8 ° C, kufanele igcinwe endaweni evalekile, ebandayo futhi engenalanga.

impilo yeshelufu
cishe iminyaka emi-2

Ubuncane be-oda Ubuningi:
1kg (ingxoxo)

Isitifiketi:I-COA, indawo yokuncibilika, i-SpecificRotation [α]D20  Sizothumela noma iyiphi idatha oyifunayo.Kodwa emikhiqizweni eyenziwe ngokwezifiso, sithumela idatha entsha kakhulu ngemuva kokuthi iphumile.
Impela, ungabona idatha ngaphambili njengereferensi.

I-D-Ls(tfa)-NCA (2)

Omqondofana

I-Semaglutide ephakathi

 

Ukupakisha kwangaphakathi

Zivame ukusetshenziselwa ukupakisha impushana.Kuya ngemfuneko yamakhasimende.Ngakho-ke, sitshele ngenkani yakho ngaphambi kokupakisha uma unezicelo ezikhethekile.

Ukupakisha kwangaphakathi 2
Ukupakisha kwangaphakathi 1
Ukupakisha kwangaphakathi 3

ukupakisha kwangaphandle

1kg kuya ku-25kg Ukupakisha kwangaphandle kunzima.Futhi kunzima ukusika nokulimaza.Ingavikela imikhiqizo yakho ngokuphelele.

Ukupakisha kwangaphandle 3
Ukupakisha kwangaphandle 2
Ukupakisha kwangaphandle 1

Izinhlelo zokusebenza

Okokuqala, uchungechunge oluseceleni lwe-semaglutide luklanywe ngokukhethekile futhi lusebenza kahle, ludlala indima ebalulekile ekusetshenzisweni kwalo kwezemithi.Lolu chungechunge oluseceleni, oluxhunywe ku-26th lysine residu ye-peptide chain, alugcini nje ukukhulisa ukuzinza kwesakhiwo se-semaglutide kodwa futhi lwenza kube lula ukusebenzisana kwayo nama-molecule athile e-biological.

Okwesibili, uchungechunge oluseceleni luhlanganisa iketango le-diacid elinamafutha angu-18, elihlanganiswa ngokuhlangana kwe-glutamic acid, ama-molecule amabili e-8-amino-3,6-dioxaoctanoic acid (AEEA), ne-octadecanedioic acid.Lesi sakhiwo esiyingqayizivele se-chain chain sandisa ukuhlangana kwe-semaglutide kwe-albumin, kunciphisa ukucaciswa kwezinso futhi kwandise isigamu sempilo yayo emzimbeni.Lo msebenzi omude uthuthukisa umphumela wokwelapha nokuqina komuthi.

Ngaphezu kwalokho, i-pegylation ye-chain chain ithuthukisa ukunyibilika nokuhamba kwe-semaglutide, ukunciphisa ukuhlunga kwezinso kanye nokuwohloka kwe-proteolytic.Lokhu kuguqulwa futhi kunciphisa i-pyrogenicity yomuthi futhi iwuvikele ekuhlaselweni kwamasosha omzimba, ukuthuthukisa ukulethwa kwezidakamizwa nokugcinwa endaweni okuhlosiwe.

imikhiqizo ehlobene

Fmoc-AEEA-OH Fmoc-AEEA-AEEA-OH I-H-Glu-OtBU I-Boc-Glu-Otbu(Osu)
I-Fmoc-L-Ser(tBu)-OH Fmoc-L-Lys-OH·HCl

Kungani Khetha Thina

1. Mayelana ne-MOQ: Singayilungisa ngokuvumelana nemfuneko yakho.
2. Mayelana nesampula: Isampula idinga imali yesampula, okungaba yimpahla ongayilanda noma ongayikhokha kithi kusengaphambili.
3. I-Mold workshop, ingenziwa ngezifiso ngokusho kwenani lamamodeli.
4. Sinikeza isevisi engcono kakhulu.Ithimba labadayisi abanolwazi selisebenzela wena.
5. Mayelana nokushintshisana: Ngicela ungithumele i-imeyili noma ungixoxele ngesikhathi esivumelana nawe.


  • Okwedlule:
  • Olandelayo:

  • Bhala umyalezo wakho lapha futhi usithumelele wona