200937-17-3 Boc-D-Leu-OH•H2O

Ukutholakala kwe-Biochemistry kanye nezidakamizwa:
Njengento ephuma ku-amino acid, i-Boc-D-Leu-OH·H2O idlala indima ebalulekile ekuhlanganiseni ama-peptide namaprotheni asebenzayo.Ukuguqulwa kwamakhemikhali kwalesi sakhi kungaholela ekwakhiweni kwezidakamizwa ezisanda kuzalwa noma abantu abazongenela izidakamizwa ekwelapheni izifo ezahlukahlukene.Izakhiwo ezihlukile ze-D-leucine zinganikeza imisebenzi ethile yebhayoloji kuma-peptide ahlanganisiwe noma amaprotheni.
I-Peptide Synthesis:
Ekuhlanganiseni kwe-peptide yesigaba esiqinile, i-Boc-D-Leu-OH · H2O iyi-monomer eyisihluthulelo ye-amino acid.Iqembu layo lokuvikela le-N-terminal Boc livumela ukuxhunyaniswa kwe-amino acid kanye nokuvikela ngaphansi kwezimo ezithambile, okuvumela ukuhlanganiswa kwamaketanga e-peptide ngokulandelana nemisebenzi ethile.
Ucwaningo Lwelabhorethri:
I-Boc-D-Leu-OH·H2O ivamise ukusetshenziswa ocwaningweni lwe-peptide synthesis kanye nesakhiwo samaprotheni.Ngokuyihlanganisa namanye ama-amino acid monomers, ukulandelana kwe-peptide okuhlukahlukene kungahlanganiswa ukuze kuphenywe ukusebenzisana kwamaprotheni-namaprotheni-ligand, kanye nokusebenza kwamaprotheni nezindlela zokulawula.
Ama-Peptide Reagents kanye Nezinsiza Zokwenziwa:
I-Boc-D-Leu-OH · H2O ingasebenza njenge-ejenti evikelayo noma i-ejenti ejiyayo ekuhlanganiseni kwe-peptide, ithuthukise ukusebenza kahle nobumsulwa benqubo yokuhlanganisa i-peptide.Ukwengeza, ingasetshenziswa njenge-reagent ye-peptide yokulebula kwe-peptide, ukuguqulwa, nokutholwa.
I-Asymmetric Synthesis:
Ngenxa yemvelo ye-chiral ye-D-leucine, i-Boc-D-Leu-OH·H2O inezinhlelo zokusebenza ezingaba khona ku-asymmetric synthesis.Ngokuyihlanganisa namanye ama-molecule e-chiral, ama-peptides namaprotheni ane-stereoconfigurations ethize angahlanganiswa ukuze kufundwe umthelela we-chirality emisebenzini yebhayoloji.