I-China 53267-93-9 Tert-butoxycarbonyl-L-Tyrosine(methyl)-OH Umkhiqizi kanye Nemboni |Jiayinglai

53267-93-9 Tert-butoxycarbonyl-L-Tyrosine(methyl)-OH Isithombe Esifakiwe

53267-93-9 I-Tert-butoxycarbonyl-L-Tyrosine(methyl)-OH

Incazelo emfushane:

Ukubukeka	Amakristalu amhlophe kuya kokumhlophe noma impushana ecwebezelayo.
MF	I-C15H21NO5
MW	295.33
Ubumsulwa	98+

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Isimo sezokuthutha&indlela yokuthumela enconyiwe:
ngomoya, ngolwandle noma nge-express

Isimo sesitoreji:
Kuvalwe endaweni eyomile, Ezinga lokushisa Legumbi

Ubuncane be-oda Ubuningi:
Ukuxoxisana

Isitifiketi:
I-COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC iyatholakala

Omqondofana

I-Boc-O-methyl-L-tyrosine;
BOC-O-METHYL-L-TYROSINE;
BOC-PHE(4-OME)-OH;BOC-P-METHOXY-PHE-OH;
I-BOC-L-TYR(ME);
BOC-L-4-METHOXYPHE;
I-BOC-4-METHOXYPHENYLALANINE;
BOC-4-METHOXY-PHE-OH

Ukupakisha kwangaphakathi

Ngokuvamile zisetshenziselwa ukupakisha impushana.Futhi zingavimbela ukukhanya kwelanga namanzi ukuba kungabi kubi.

ukupakisha kwangaphandle

Ibhokisi eliqinile lingavikela imikhiqizo yakho ukuthi ingaphahlazeka futhi ibe manzi.

Izinhlelo zokusebenza

Ikhadi i-bei oxytocin (i-Carbetocin) iwuhlobo lokuhlanganiswa kokusebenza isikhathi eside okunezici zokuqukethwe kwe-agonist oxytocin 8 peptide, izakhiwo zayo zomtholampilo nezemithi ezifana nokukhiqiza kwemvelo i-oxytocin.Njenge-oxytocin, i-cabetin ibophezela kuma-oxytocin receptors emsipha obushelelezi wesibeletho, okubangela ukufinyela okunesigqi kwesibeletho, okwandisa ukuvama kwaso futhi kwandise ukushuba kwesibeletho phezu kokufinyela kwasekuqaleni.Amazinga ama-oxytocin receptors esibelethweni aphansi ngesikhathi sokukhulelwa futhi anda ngesikhathi sokukhulelwa, afinyelela phezulu ngesikhathi sokuzalwa.Ngakho-ke, i-cabetin ayinawo umthelela esibelethweni esingakhulelwe, kodwa inokufinyezwa okusebenzayo kwesibeletho esikhulelwe kanye nesibeletho ngemva kokuzalwa.Kuphakathi kwe-intravenously noma ngaphakathi, isibeletho sifinyela ngokushesha, sifinyelele amandla aqondile phakathi nemizuzu emi-2.Umthamo owodwa we-capetin efakwe emthanjeni uyasebenza esibelethweni cishe ihora elilodwa, okwanele ukuvimbela ukopha kwangemva kokubeletha ngokushesha ngemva kokubeletha.Imvamisa kanye nobukhulu bokufinyela ngemuva kokuphathwa kwe-carpetin kwangemva kokubeletha kwakunde kune-oxytocin.Ucwaningo luye lwabonisa ukuthi lapho unikezwa umthamo owodwa we-100μg emithanjeni ngokushesha ngemva kokuhlinzwa ngaphansi kwe-epidural noma i-lumbar anesthesia, i-carbetin iphakeme kakhulu kune-placebo ekuvimbeleni i-hypotonia yesibeletho kanye nokunciphisa ukopha kwangemva kokubeletha.I-Carpeine enikezwe esikhathini sokuqala kwangemva kokubeletha ingase futhi ikhuthaze ukululama kwesibeletho.
I-Cabetin ibophezela kuma-oxytocin receptors emsipha obushelelezi wesibeletho ukuze ibangele ukuthi isibeletho sifinyezeke ngendlela enesigqi, okwandisa ukufinyela kwaso futhi kwandise ukushuba kwesibeletho.Umthamo owodwa we-carbetin unganikezwa ngokushesha ngemva kokubeletha ukuvimbela ukopha kwangemva kokubeletha.Kutholakale ukuthi umjovo we-oxytocin ngemuva kokubeletha uhlanganiswe nokuphathwa kwe-cabetin kungavimbela ngempumelelo ukulahleka kwegazi kwangemva kokubeletha.Ngemuva kwesigaba sokuhlinzwa, ukusetshenziswa kwe-cabetin kuhlanganiswe ne-oxytocin kungaqinisa ukufinyela kwesibeletho, ukunciphisa inani lokulahlekelwa kwegazi ngemva kwesigaba sokuhlinzwa, umphumela ungcono nakakhulu kune-hemabate.Kwabesifazane abane-cicatritic uterus, i-placenta previa nezinye izici eziyingozi kakhulu zokopha kwangemva kokubeletha, i-carbetin ingavimbela ngempumelelo ukuvela kokuphuma kwegazi kwangemva kokubeletha.Isetshenziselwa i-elective epidural noma i-lumbar anesthesia ngemva kwesigaba sokuhlinzwa ukuvimbela ubuthakathaka bokufinyela kwesibeletho kanye nokuphuma kwegazi kwangemva kokubeletha.

imikhiqizo ehlobene

I-Boc-Gly-Tyr-OH	I-Boc-L-Tyr-Obzl	L-Tyr(mina)	Cbz-L-Tyr-OH
I-Boc-Gly-Tyr-OMe	I-Boc-L-Tyr(tBu)-OH	L-Tyr(mina).Hcl	Cbz-D-Tyr-OH
I-Gly-L-Tyr-OH	I-Boc-Tyr(bzl)-OH	I-D-Tyr(bzl).Hcl	Cbz-N-Me-Tyr(tbu)-OH
I-Gly-L-Tyr-OH	I-Boc-D-Tyr(bzl)-OH	I-D-Tyr(Et).HCl	cbz-L-Tyr-Ome
I-Fmoc-β-Ala-D-Tyr (Et)	Boc-L-Tyr(mina)-OH	I-L-Tyr(bzl)-obzl.Hcl	Cbz-L-Tyr(Et)-OH
I-Val-Tyr-OH	Boc-D-Tyr(mina)-OH	I-L-Tyr(tbu)-OH	I-Z-Tyr(tbu)
Cbz-L-Val-Tyr-OH	Boc-Tyr (Kodwa).Aib	I-L-Tyr-OL.Hcl	Z-Tyr(bzl)-OH
Cbz-L-Val-Tyr-Ome	Fmoc-L-Tyr-OH	I-D-Tyr-Ome.Hcl	Z-Tyr(tbu).DCHA
Ile-Tyr	I-Fmoc-N-Me-Tyr(tBu)-OH	L-Tyr(bzl)-Ome.Hcl	I-Tyr-Phe
Boc-Ile-Tyr	FMOC-N-Me-D-Tyr(mina)-OH	I-L-Tyr-Oet-OH	I-Tyr-Asp
I-Tyr-Pro-Otbu	I-Fmoc-N-Me-D-Tyr(tBu)-OH	I-D-Tyr-Oet•HCl	I-Arg-Tyr-Oet
L-Phe-Tyr-OH	I-Fmoc-N-Me-L-Tyr(bzl)-OH	I-L-Tyr-Ome.HCl	Cbz-L-Ser-Tyr
I-Boc-L-Phe-Tyr-OH	I-Fmoc-L-Tyr-Ome	I-HL-Tyr-Oet.Hcl	I-Tyr(bzl) -obzl
L-Tyr-OH	I-Fmoc-L-Tyr(Cbz)	I-Ac-D,L-Tyr-OH	I-Boc-N-Me-D-Tyr(bzl)-OH
I-D-Tyr-OH	Fmoc-L-Tyr(bzl)-oh	AC-L-Tyr-OH	I-Boc-N-Me-L-Tyr(tbu)-OH
I-DL-Tyr	I-Fmoc-L-Tyr(Et)-OH	I-N-Ac-L-Tyr-Oet	I-Boc-L-Tyr-OL
N-Me-Tyr (mina)-OH	I-Fmoc-L-Tyr(tBu)-OH	L-Tyr-Otbu	I-Boc-D-Tyr(bzl)-OL
I-N-Me-Tyr (mina).HCL	Fmoc-L-Tyr(mina)	I-D-Tyr-Otbu	I-Boc-L-Tyr(bzl)-Ol
I-L-Tyr-NCA	Fmoc-L-Tyr(mina)-tyr (mina)	I-L-Tyr-Obzl	Boc-L-Tyr(mina)-OL
I-D-Tyr-NCA	Fmoc-D-Tyr(mina)-OH	I-L-Tyr-obzl-Tos-OH	Boc-Tyr(Et).OL
I-Tyr(bzl)-NCA	I-Fmoc-D-Tyr(Et)-OH	I-Boc-L-Tyr-OH	I-Boc-L-Tyr-Ome
I-Tyr(bzl)-NCA	I-Fmoc-D-Tyr(Et)-D-Tyr (Et)	I-Boc-D-Tyr-OH	I-Boc-D-Tyr-Ome
L-Tyr(Et)-OH	I-Fmoc-D-Tyr(tbu)-OH	I-Boc-DL-Tyr-OH	Boc-Tyr-Otbu
I-Boc-L-Tyr(Et)-OH	I-Boc-DL-Tyr-Otbu	I-Boc-L-Tyr-Oet	I-Boc-D-Tyr-Otbu
I-Boc-D-Tyr(Et)-OH	I-Boc-N-Me-L-Tyr(bzl)-OH

Ukuphakama

1. Isevisi ye-R&D iyatholakala
2. Umkhiqizi oqinisekisiwe we-ISO, isiqinisekiso sekhwalithi
I-3.Inkambo ephelele yenkonzo yokulandelela ngesikhathi sokukhiqiza
I-4.Izindleko eziphezulu
5.Imibhalo yesitifiketi sekhwalithi enikeziwe ngokwesicelo sekhasimende ngalinye
I-6.Isevisi enhle emva kokuthengisa, ukugcina ubuhlobo obuseduze nekhasimende
7.Insiza egcwele yokusiza ukwehlisa izindleko zokuthumela
8.Isampula yamahhala enikelwe ukuhlola ikhwalithi ngaphambi kwanoma iyiphi inkokhelo
9.Isikhathi sokukhokha okuxoxiswana ngaso
10.Amakhasimende e-Assit abhekana nezindaba zaseShayina