I-Peptide Synthesis: I-Boc-D-Ser-OMe idlala indima ebalulekile ekuhlanganiseni kwe-peptide.Ingahlanganiswa namanye ama-amino acid ukuze kwakheke amaketanga e-peptide ngokulandelana nezakhiwo ezithile.Iqembu lokuvikela le-Boc liqinisekisa ukusabela okukhethiwe nokulawulwayo, lenza ukuhlanganiswa okunembile kwama-peptide.Lokhu okuphuma ku-amino acid kuvame ukusetshenziswa ekuhlanganiseni kwe-peptide yesigaba esiqinile ukuze kwakhiwe ama-peptide anemisebenzi efiselekayo yebhayoloji.
Ukutholwa Kwezidakamizwa: I-Boc-D-Ser-OMe ithola izinhlelo zokusebenza ocwaningweni lokutholwa kwezidakamizwa.Ukwethulwa kwayo kuma-molecule ezidakamizwa kungaholela ekwakhiweni kwezindlela zokwelapha ezintsha ezinezinzuzo ezingaba khona zokwelapha.Ukucushwa kwe-D kwe-serine kungase kunikeze izakhiwo eziyingqayizivele emthini, njengokuzinza okuthuthukisiwe, ukukhetha, noma iphrofayili ye-pharmacokinetic.Le mithi ingase isetshenziselwe ukwelapha izifo ezihlukahlukene, kuhlanganise nomdlavuza, ukuphazamiseka kwemizwa, nezifo ezithathelwanayo.
Izifundo zamakhemikhali ezinto eziphilayo: I-Boc-D-Ser-OMe iyithuluzi elibalulekile ocwaningweni lwamakhemikhali ezinto eziphilayo, ikakhulukazi ekuhloleni imisebenzi nokusebenzelana kwamaphrotheni aqukethe i-serine.Ngokuhlanganisa lokhu kuphuma kokuphuma kwe-amino acid kuma-peptide asetshenziswa njengama-probes noma ama-inhibitors, abacwaningi bangathola ukuqonda mayelana nezinqubo zezinqubo zebhayoloji ezihlobene ne-serine.
I-Bioconjugation: I-Boc-D-Ser-OMe ingasetshenziswa ekuphenduleni kwe-bioconjugation ukuxhumanisa ama-peptide noma amaprotheni kwamanye ama-molecule e-biological.Ukusebenza kwe-methyl ester kuvumela ukunamathiselwa kwe-covalent kumasosha omzimba, ama-carbohydrate, noma amanye ama-peptide, ukudala amasistimu okulethwa okuhlosiwe, ama-biosensors, noma amanye ama-bioactive conjugates anokusebenza okuthuthukisiwe.