isibhengezo_sekhasi

I-Fmoc-L-Gln(Trt)-Aib-OH

I-Fmoc-L-Gln(Trt)-Aib-OH

Incazelo emfushane:

Ukubukeka Impushana emhlophe ukuya kokumhlophe
MF
MW
Ubumsulwa 98+


Imininingwane Yomkhiqizo

Isimo sezokuthutha
Ingathuthwa ngezinga lokushisa elivamile.

Ncoma indlela yokuthumela
ngomoya, ngomhlaba noma ngolwandle

Isimo sesitoreji:
2-8 ° C, kufanele igcinwe endaweni evalekile, ebandayo futhi engenalanga.

impilo yeshelufu
cishe iminyaka emi-2

Ubuncane be-oda Ubuningi:
1kg (ingxoxo)

Isitifiketi:I-COA, indawo yokuncibilika, i-SpecificRotation [α]D20  Sizothumela noma iyiphi idatha oyifunayo.Kodwa emikhiqizweni eyenziwe ngokwezifiso, sithumela idatha entsha kakhulu ngemuva kokuthi iphumile.
Impela, ungabona idatha ngaphambili njengereferensi.

I-D-Ls(tfa)-NCA (2)

Omqondofana

I-Fmoc-L-Gln(Trt)-Aib-OH

Ukupakisha kwangaphakathi

Zivame ukusetshenziselwa ukupakisha impushana.Kuya ngemfuneko yamakhasimende.Ngakho-ke, sitshele ngenkani yakho ngaphambi kokupakisha uma unezicelo ezikhethekile.

Ukupakisha kwangaphakathi 2
Ukupakisha kwangaphakathi 1
Ukupakisha kwangaphakathi 3

ukupakisha kwangaphandle

1kg kuya ku-25kg Ukupakisha kwangaphandle kunzima.Futhi kunzima ukusika nokulimaza.Ingavikela imikhiqizo yakho ngokuphelele.

Ukupakisha kwangaphandle 3
Ukupakisha kwangaphandle 2
Ukupakisha kwangaphandle 1

Izinhlelo zokusebenza

Ukusetshenziswa kwe-Fmoc-L-Gln(Trt)-Aib-OH kuhlukile futhi kubamba inani elibalulekile emikhakheni ehlukahlukene.Nakhu ukuhlukaniswa kwezinhlelo zokusebenza eziyinhloko:
I-Peptide Synthesis:
I-Fmoc-L-Gln(Trt)-Aib-OH isebenza njengebhlokhi yokwakha ebalulekile ekuhlanganiseni kwe-peptide yesigaba esiqinile.Inhlanganisela yayo eyingqayizivele yamaqembu okuvikela e-Fmoc kanye ne-Trt iqinisekisa ukuzinza nokuncibilika, okuvumela ukuhlangana okunembile kwamaketanga e-peptide.
Ukufakwa kwe-amino acid engeyona eyemvelo i-Aib (i-α-aminoisobutyric acid) ivumela ukwethulwa kokulandelana okuyingqayizivele nemisebenzi engaba khona yezinto eziphilayo.
Ubunjiniyela bamaprotheni kanye nokuguqulwa:
Lokhu kokuphuma kokunye kungasetshenziswa ukuze kuhlanganiswe noma kuguqule amaprotheni ngokulandelana okuqondile kwe-amino acid, okuvumela ukucwaninga kwesakhiwo nokusebenza kwamaprotheni.
Ukwethulwa kwe-Aib kungashuna kahle izakhiwo zephrotheni njengokuzinza, umsebenzi we-enzymatic, noma ukusebenzisana namanye ama-molecule.
Ukutholwa Kwezidakamizwa Nokuklama:
Ama-Peptide aqukethe i-Fmoc-L-Gln(Trt)-Aib-OH angahlolelwa amandla awo okwelapha, okubenza babe abantu ababalulekile ekuthuthukisweni kwezidakamizwa.
Ukulandelana okuqondile kwe-amino acid kanye nokuba khona kwe-Aib kungathuthukisa ubuhlobo obubophezelayo nokukhetha kuma-molecule okuqondiwe.
I-Biological Probes nama-ejenti wokufanekisa:
Izici ezihlukile ze-Fmoc-L-Gln(Trt)-Aib-OH ziyenza ifanelekele ukuthuthukisa ama-biological probe nama-imaging agents.
Lawa ma-probe angasetshenziswa ukutadisha izinqubo zebhayoloji, ukuthola ukusebenzisana kwamangqamuzana, noma ukusiza ekuxilongeni kokuqala kwezifo.
Izinjongo Zocwaningo Nezemfundo:
Ngenxa yokwakheka kwayo okulula kanye nezakhiwo ezizinzile, i-Fmoc-L-Gln(Trt)-Aib-OH ivame ukusetshenziswa ocwaningweni oluyisisekelo nokuhlolwa kwezemfundo ku-biochemistry kanye ne-organic chemistry.
Isiza abafundi nabacwaningi ukuthi baqonde kangcono futhi bazi kahle izimiso nezindlela zokwenziwa kwe-peptide kanye nobunjiniyela bamaprotheni.

imikhiqizo ehlobene

Boc-Gly-Ile-OH L-Ile-OH D,L-Ile-OH N-Me-L-Ile-OH
Boc-L-Ile-OH Fmoc-L-Ile-OH Fmoc-LN-Me-Ile-OH Cbz-L-Ile-OH
2-Aib-Ome.Hcl Boc-L-Aib-OH Fmoc-L-Aib-OH

Kungani Khetha Thina

1. Mayelana ne-MOQ: Singayilungisa ngokuvumelana nemfuneko yakho.
2. Mayelana nesampula: Isampula idinga imali yesampula, okungaba yimpahla ongayilanda noma ongayikhokha kithi kusengaphambili.
3. I-Mold workshop, ingenziwa ngezifiso ngokusho kwenani lamamodeli.
4. Sinikeza isevisi engcono kakhulu.Ithimba labadayisi abanolwazi selisebenzela wena.
5. Mayelana nokushintshisana: Ngicela ungithumele i-imeyili noma ungixoxele ngesikhathi esivumelana nawe.


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