I-China 122235-70-5 BOC-DAP(FMOC)-OH Umkhiqizi kanye Nemboni |Jiayinglai

122235-70-5 BOC-DAP(FMOC)-OH

Incazelo emfushane:

Ukubukeka	Impushana emhlophe ukuya kokumhlophe
MF	I-C23H26N2O6
MW	426.46
Ubumsulwa	98+

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Isimo sezokuthutha&indlela yokuthumela enconyiwe:
ngomoya, ngolwandle noma nge-express

Isimo sesitoreji:
2-8°C

Ubuncane be-oda Ubuningi:
Ukuxoxisana

Isitifiketi:
I-COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC iyatholakala

Omqondofana

I-Boc-3-(Fmoc-amino)-L-alanine,Nα-Boc-Nβ-Fmoc-L-2,3-diaminopropionicacid;

I-NALPHA-tert-Butoxycarbonyl-NB-9-fluorenylmethoxycarbonyl-L-2,3-diaminopropi;

N-.ALPHA.-BOC-N-.BETA.-FMOC-L-2,3-DIAMIOPROPIONICACID;

I-N-Boc-N-Fmoc-(S) -2,3-diaminopropionicacid;

I-N-α-Boc-N-β-Fmoc-L-2,3-diamiopropionicacid;

(S) -2,3-Diaminopropanoicacid,N2-BOC,N3-FMOCivikelwe;

3-[(9H-Fluoren-9-ylmethoxycarbonyl)amino]-L-alanine,N-BOCVikelwe;

I-Boc-Dapa(FMoc)-OH

Ukupakisha kwangaphakathi

Ngokuvamile zisetshenziselwa ukupakisha impushana.Futhi zingavimbela ukukhanya kwelanga namanzi ukuba kungabi kubi.

ukupakisha kwangaphandle

Ibhokisi eliqinile lingavikela imikhiqizo yakho ukuthi ingaphahlazeka futhi ibe manzi.

Izinhlelo zokusebenza

Ama-amino acid avikela kabili ikakhulukazi ahlanganisa i-D-lys-OH equkethe amaqembu e-amino echungechunge oluseceleni kanye neketango eliqukethe iketangopukujikeleza kwe-L-Rag-OH.Eqenjini le-AA-amin, isu lokuvikela i-FMOC lisamukelwa, kanti umalume wesibili we-carbonate emibili usetshenziswa ochungechungeni oluseceleni.I-Tibon yethulwa eqenjini lamapayipi e-oxygenyl ukuvikela i-Fu Fu 5 ~ Sulfidal ukuze ivikele.Ngoba kunezinyathelo eziningi zokuhlanganisa zalawa ma-amino acid amabili, impendulo eyinhloko yempendulo eyinhlokosama-teps enza izivivinyo zokuthuthukisa isici esisodwa.Ukuvikelwa kwe-D-LYS-OH ikakhulukazi kubheka isikhathi esithinta isizukulwane sokulingana kwethusiiizinga lokushisa, nesikhathi sokukhumula ithusi.Ukuvikelwa kwe-L-Rag-OH ikakhulukazi kubheka ukulungiswa kwe-Z-RG-OH. Ngaleso sikhathi, izinga lokushisa le-ZL-Rag (PBF) -OH likasawoti we-ammonia, kanye nenani le-catalyst lapho i-hydrogen ihlanganiswe no-Z,tukucindezela kwakhe, izinga lokushisa kanye nesikhathi sokusabela kuthole umphumela omuhle ngokuhlolwa kokwenza kahle.

Phakathi nenqubo yokusabela, inqubo yokusabela kokutholwa kwe-TL.C iyamukelwa ngokuyinhloko, futhi izimo zecrystallization zomkhiqizo ziyathuthukiswa.

Ukuhlanzeka komkhiqizo kukalwa nge-chromatography ye-liquid esebenza kahle kakhulu, futhi ubumsulwa bomkhiqizo bufinyelele ngaphezu kwama-95.0%.Ngaphezu kwezimpawu ezijwayelekile zomzimba ezingaguquki, futhiikuhlanganisa i-infrared spectrum, mass spectrum noma i-hydrogen spectrum.

imikhiqizo ehlobene

I-Boc-D-Dap(Boc).DCHA	I-Boc-Dap(Boc)-OH.DCHA	I-Boc-D-Dap(Fmoc)-OH	I-Boc-Dap(Cbz)-OH
I-Boc-D-Dap(Cbz)-OH	I-Fmoc-L-Dap(Fmoc)-OH	I-Fmoc-L-Dap(Cbz)-OH	I-Fmoc-D-Dap(cbz)
I-Cbz-D-Dap(BOC)-OH	I-Cbz-L-Dap(Fmoc)-OH

Ukuphakama

1. Isevisi ye-R&D iyatholakala
2. Umkhiqizi oqinisekisiwe we-ISO, isiqinisekiso sekhwalithi
I-3.Inkambo ephelele yenkonzo yokulandelela ngesikhathi sokukhiqiza
I-4.Izindleko eziphezulu
5.Imibhalo yesitifiketi sekhwalithi enikeziwe ngokwesicelo sekhasimende ngalinye
I-6.Isevisi enhle emva kokuthengisa, ukugcina ubuhlobo obuseduze nekhasimende
7.Insiza egcwele yokusiza ukwehlisa izindleko zokuthumela
8.Isampula yamahhala enikelwe ukuhlola ikhwalithi ngaphambi kwanoma iyiphi inkokhelo
9.Isikhathi sokukhokha okuxoxiswana ngaso
10.Amakhasimende e-Assit abhekana nezindaba zaseShayina